Product Details
Catalog Number: RA24604
Applications: IHC
Type: Rabbit IgG
Immunogen: Synthetic oxytocin coupled to bovine thyroglobulin (BTg) with carbodiimide (CDI) linker.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Whole serum
Format B: lyophilized
Species Reactivity: Rat
Entrez: 5020
UniProt: P01178
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$302.50Add to Cart

Oxytocin is a mammalian hormone that acts primarily as a neuromodulator in the brain. The receptor is a G-protein-coupled receptor which requires Mg2+ and cholesterol. It belongs to the rhodopsin-type (class I) group of G-protein-coupled receptors. Oxytocin receptors are expressed by neurons in many parts of the brain and spinal cord, including the amygdala, ventromedial hypothalamus, septum, nucleus accumbens and brainstem.

It is invlolved in regulating mood including perceptions of stress and stress induced depression. Oxytocin may play a role in autism and may be an effective treatment for related repetitive and affiliative behaviors. It is also know to produce antinociception and analgesia making it a target for certain pain therapies.

Images

Oxytocin staining of Rat Hypothalamus (PVN/SON). Note: staining is completely eliminated by pretreatment of 1 mL of the diluted antibody with 5 μg of Oxytocin. Pretreatment of 1 mL of the diluted antibody with as much as 100 μg of vasopressin does not diminish staining.

Oxytocin staining of Rat Hypothalamus (PVN/SON). Note: staining is completely eliminated by pretreatment of 1 mL of the diluted antibody with 5 μg of Oxytocin. Pretreatment of 1 mL of the diluted antibody with as much as 100 μg of vasopressin does not diminish staining.