Product Details
Catalog Number: RA25016
Applications: WB
Type: Rabbit IgG
Immunogen: A synthetic peptide within an internal region [residues 100-200] of the mouse GPI-anchored HDL-binding protein 1 protein. [Swiss-Prot# Q9D1N2].
Storage: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Mouse, Rat
Entrez: 388328
UniProt: Q8IV16
Downloads: Datasheet (pdf)
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100 ul$379.00Add to Cart

GPI-anchored HDL-binding protein 1 (Gpihbp1) is a novel protein that may be involved in the regulation of the delivery of fats to cells for energy and storage. Digested fats travel to the small intestine, where they are packaged into chylomicrons (particles filled with triglycerides). Chylomicrons then travel through the bloodstream and deliver triglycerides to tissues that are hungry for fuel or to adipose tissue for energy storage. Triglycerides are broken down or hydrolyzed by the enzyme lipoprotein lipase (LpL). The triglyceride breakdown products are then taken up and used by cells. Gpihbp1 is the molecule in capillaries that facilitates the capture of chylomicrons and facilitates the interaction with LpL. It has been shown that fats in the bloodstream are not readily metabolized in the absence of GPIHBP1.

Images

Detection of Gpihbp1 in transfected lysate (Lane 1). An empty vector lysate was used as a negative control (Lane 2).

Detection of Gpihbp1 in transfected lysate (Lane 1). An empty vector lysate was used as a negative control (Lane 2).