Product Details
Catalog Number: RA25019
Applications: WB, IHC
Type: Rabbit IgG
Immunogen: A synthetic peptide made to an internal region within residues 500-600 of the human protein.
Storage: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat, Chicken
Entrez: 4976
UniProt: O60313
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ul$245.00Add to Cart

This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Eight transcript variants encoding different isoforms, resulting from alternative splicing of exon 4 and two novel exons named 4b and 5b, have been reported for this gene.

Supporting Products
NameCatalog #Size
OPA1P2501950 ul. Blockig Peptide
Images

OPA1 staining of prostatic smooth muscle and glandular epithelium. 40X Magnification.

OPA1 staining of prostatic smooth muscle and glandular epithelium. 40X Magnification.

Detection of Opa-1 protein in post-nuclear extracts of mouse embryonic fibroblasts.

Detection of Opa-1 protein in post-nuclear extracts of mouse embryonic fibroblasts.