Product Details
Catalog Number: RA25046
Applications: ICC, WB, IHC
Type: Rabbit IgG
Immunogen: Synthetic peptide (Rat) from the N-terminal extracellular domain conjugated to immunogenic carrier protein.
Storage: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Whole serum
Format B: lyophilized
Species Reactivity: Mouse, Rat
Entrez: 55662
UniProt: Q9NWT6
Downloads: SDS (pdf)
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ul$379.00Add to Cart

Factor Inhibiting HIF1 (FIH) protein facilitates repression of HIF-1 transcriptional activity by binding to VHL, which acts as a transcriptional corepressor. VHL inhibits HIF-1 alpha transactivation function by recruiting histone deacetylases. Involvement of VHL in association with FIH provides a unifying mechanism for the modulation of HIF-1 alpha protein stabilization and transcriptional activation in response to changes in cellular oxygen concentration.

Images

Factor Inhibiting HIF1 staining of rat brain tissue (dilution: 1:100).

Factor Inhibiting HIF1 staining of rat brain tissue (dilution: 1:100).

Detection of Factor Inhibiting HIF-1 by Western Blot.

Detection of Factor Inhibiting HIF-1 by Western Blot.