Product Details
Catalog Number: RA25069
Applications: WB, IHC
Type: Rabbit IgG
Immunogen: Synthetic peptide made to an internal portion of the mouse protein (within residues 350-400). [Swiss-Prot# Q9R207].
Storage: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Entrez: 4683
UniProt: O60934
Downloads: Datasheet (pdf)
Downloads: SDS (pdf)
Product Sizes
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100 ul$379.00Add to Cart

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.

Images

NBS1 Antibody-Western Blot on NIH/3T3 (Lane 4) and HeLa whole cell extract (Lane 5).

NBS1 Antibody-Western Blot on NIH/3T3 (Lane 4) and HeLa whole cell extract (Lane 5).

NBS1 staining of paraffin-embedded mouse bone marrow.

NBS1 staining of paraffin-embedded mouse bone marrow.