Collagen-1 (also known as collagen alpha, COL1A1, and alpha-1 type I collagen) is the largest component of fibrillar collagen found in cartilage and connective tissues, and synthesizes by fibroblasts, osteoblasts, and odontoblasts. Trimers are formed by combing two alpha one chains and one alpha 2 chain. Mutations of the gene are found in Ehlers-Danlos syndrome, as well as osteogenesis imperfecta. Over 50 mutations have been found in these diseases, including deletions, insertions, splice variants, and substitutions.
- Product Reviews
- Product Publications
If you've used this product in a publication, let us know. Email email@example.com, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Name Catalog # Size Calcium Sensing Receptor MO25048 100 ul Collagen IV MO47018 100 ul COX-2 (Cyclooxygenase-2) MO47062 100 ul EWSR1 MO22168 100 ul MiTF (Microphthalmia-Associated Transcription Factor) MO47034 0.5 ml Myogenin (Myogenic Factor 4)/MYOG MO47054 100 ul Osteopontin MO25049 100 ul p63 (Tumor Protein p63) MO47058 100 ul Parvalbumin CH22119 100 ul TGF beta MO20012 100 ul. Transcription Factor E3 (TFE3) MO47007 100 ul