Collagen-1 (also known as collagen alpha, COL1A1, and alpha-1 type I collagen) is the largest component of fibrillar collagen found in cartilage and connective tissues, and synthesizes by fibroblasts, osteoblasts, and odontoblasts. Trimers are formed by combing two alpha one chains and one alpha 2 chain. Mutations of the gene are found in Ehlers-Danlos syndrome, as well as osteogenesis imperfecta. Over 50 mutations have been found in these diseases, including deletions, insertions, splice variants, and substitutions.
- Product Reviews
- Product Publications
If you've used this product in a publication, let us know. Email firstname.lastname@example.org, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Name Catalog # Size BMP-2 Inducible Kinase (BIKE) RA30004 50 ug BMP-2/4 GT15053 100 ug BMP-7 MO15079 100 ug BMP-7 MO15079 500 ug BMP-8 GT15161 100 ug Calcium Sensing Receptor MO25048 100 ul COX-2 GT15206 100 ug COX-2 RA18005 100 ul Osteocalcin MO15128 100 ul Osteopontin MO25049 100 ul Parvalbumin CH22119 100 ul RUNX2 GT15188 100 ug SMAD1 GT15219 100 ug TGF beta MO20012 100 ul. TGF-beta3 GT15074 100 ug TNF alpha GT15113 100 ug