Human Von Willebrand Factor(factor VIII R:Ag) is a 270 kDa multimeric plasma gylcoprotein. It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation factor VIII. The von Willebrand factor has functional binding domains to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. The factor is synthesized by endothelial cells and is also present in platelets and megakaryocytes.
ThisRRA antibody specifically reacts with the cytoplasm of human endothelial cells from normal and neoplastic blood and from lymphatic vessels. It also reacts with human endocardium, platelets and megakaryocytes. It may be used for immunohistological studies of the vascular structures in frozen tissue preparations and enzymatically pre-digested, formalin, methacarn, Bouin's or ethanol-fixed and paraffin-embedded tissue sections.
- Product Reviews
- Product Publications
If you've used this product in a publication, let us know. Email firstname.lastname@example.org, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Name Catalog # Size Actin GT15248 100 ug Actin MO22125 100 ug CD146/MCAM MO30005 50 ug CD31/PECAM-1 GT15190 100 ug GFAP CH22102 100 ul GFAP CH23011 200 ul GFAP MO15052 100 ul GFAP MO22136 100 ul GFAP MO45001 100 ug GFAP RA22101 100 ul Glial Fibrillary Acidic Protein (GFAP) MO22101 100 ul GLUT1 RA25078 100 ul GLUT1 (Glucose Transporter Type I)/SCL2A1 MO47056 100 ul JAM-A GT15249 100 ul JAM-A MO15149 100 ug Nestin MO15012 100 ug Occludin MO15148 100 ug VCAM-1/CD106 GT15251 100 ug VCAM-1/CD106 MO15171 100 ug VCAM1/CD106 MO30006 50 ul ZO-1/TJP1 GT30002 100 ul