Product Details
Catalog Number: RA25102
Applications: ICC, IHC, IF
Type: Rabbit IgG
Dilutions: Immunohistochemistry: 1:1,000 Immunofluorescent: 1:1,000 Immunocytochemistry: 1:1,000
Immunogen: Purified antisera of the Von Willebrand Factor (factor VIII R:ag) related antigen in plasma.
Storage: Antibody can also be aliquotted and stored frozen at -20° C long term. The antibody can be stored at 2° - 8° C for the short term without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 7450
UniProt: P04275
Downloads: Datasheet (pdf)
Product Sizes
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0.1 ml$445.00Add to Cart

Human Von Willebrand Factor(factor VIII R:Ag) is a 270 kDa multimeric plasma gylcoprotein. It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation factor VIII. The von Willebrand factor has functional binding domains to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. The factor is synthesized by endothelial cells and is also present in platelets and megakaryocytes.

ThisRRA antibody specifically reacts with the cytoplasm of human endothelial cells from normal and neoplastic blood and from lymphatic vessels. It also reacts with human endocardium, platelets and megakaryocytes. It may be used for immunohistological studies of the vascular structures in frozen tissue preparations and enzymatically pre-digested, formalin, methacarn, Bouin's or ethanol-fixed and paraffin-embedded tissue sections.

Images
Immunocytochemistry

Immunofluorescence analysis using Von Willebrand Factor antibody (RA25102).

Immunocytochemistry

Immunofluorescence analysis using Von Willebrand Factor antibody (RA25102).

Immunohistochemistry

Formalin fixed paraffin embedded human tonsil stained with RA25102 antibody.

Immunohistochemistry

Formalin fixed paraffin embedded human tonsil stained with RA25102 antibody.