Catalog Number: RA30062
Applications: WB, IHC
Type: Rabbit IgG
Immunogen: KLH-conjugated synthetic peptide corresponding to to amino acids at the C-terminus of human CARD8.
Storage: Store at 4°C. Do not freeze.
Shipping: Refrigerated (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
CARD8, a novel CARD-containing protein, was recently identified. This protein interacts with DRAL, a p53-responsive protein implicated in the induction of apoptosis, and caspase-1 and its related proteins ICEBERG and pesudo-ICE. CARD8 potently inhibits NF-kB signaling, which plays a key role in inﬂammation, and may contribute to avoid a pathologic activation of NF-kB.
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