Product Details
Catalog Number: RA34005
Applications: WB, IHC, E
Type: Rabbit IgG
Immunogen: Synthesized peptide derived from human Tau around the phosphorylation site of T534. Immunogen Region:150-230aa
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat
Downloads: Datasheet (pdf)
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100 ul$245.00Add to Cart

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Specificity: Phospho-Tau (T534) Polyclonal Antibody detects endogenous levels of Tau protein only when phosphorylated at T534.

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