Product Details
Catalog Number: RA34012
Applications: WB, IHC
Type: Rabbit IgG
Immunogen: Recombinant protein of human MBP
Storage: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat
Entrez: 4155
UniProt: P02686
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ul$329.00Add to Cart

MBP belongs to the myelin basic protein family. The classic group of MBP isoforms (isoform 4-isoform 14) are the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. This is a rabbit polyclonal antibody raised against the full-length of human MBP, and is capable of recognizing multiple isoforms of MBP.

Images

Immunohistochemistry of paraffin-embedded rat kidney using MBP antibody at dilution of 1:200 (400x lens).

Immunohistochemistry of paraffin-embedded rat kidney using MBP antibody at dilution of 1:200 (400x lens).