Product Details
Catalog Number: GT30000
Applications: WB, IHC, E
Type: Goat IgG
Immunogen: C Terminus of DKK1: peptide sequence (CDHHQASNSSRLHT).
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
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50 ug$365.00Add to Cart

DKK1 is a secreted factor that has been linked to the function of osteoblasts. Elevated DKK1 levels in bone marrow plasma and peripheral blood from patients with multiple myeloma correlated with the gene-expression patterns of DKK1 and were associated with the presence of focal bone lesions. The production of DKK1, an inhibitor of osteoblast differentiation, by myeloma cells is associated with the presence of lytic bone lesions in patients with multiple myeloma.

Image: DKK1 staining of Placenta Tissue. Formalin-Fixed Paraffin-Embedded (FFPE).