Product Details
Catalog Number: GT41001
Applications: IHC
Type: Goat IgG
Format A: liquid
Species Reactivity: Human, Rat, Primate, Bovine, Dog, Equine
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$310.00Add to Cart
Alsin2 specifically binds to, and functions as a guanine nucleotide exchange factor (GEF) for the small GTPase RAB5.It  contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics.

Image:Alsin (dilution: 3.8µg/ml)staining of human brain tissue, cortex (formalin-fixed paraffin-embedded) at 5 ug/ml followed by biotinylated horse anti-goat IgG secondary antibody,  alkaline phosphatase-streptavidin and chromogen.Protocol on data-sheet.