Product Details
Catalog Number: GT41015
Applications: IHC, E
Type: Goat IgG
Immunogen: Synthetic peptide: Peptide with sequence: TSLPLGVKVEDS-C, from the N Terminus of the protein sequence according to NP_002439.1.
Storage: Antibody can be aliquotted and stored frozen at -20° C to -70° C in a manual defrost freezer for six months without detectable loss of activity. The antibody can be stored at 2° - 8° C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
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100 ug$310.00$250.00Add to Cart

MSX1 is a transcriptional repressor that belongs to the Msh homeobox family. It plays a role in cranofacial development and, via a onic hedgehog-controlled cascade that includes MSX1 acts in parallel with the Wnt1 network, establishes the midbrain dopaminergic progenitor domain, which gives rise to a neuronal population that is critical for normal function of the human brain. It is an excellent marker for this population of neural progenitors.

Pathologies in dopaminergic neurons result in a number of neurological diseases inclusing Parkinson's Disease.

Image: MSX1 staining of staining of paraffin embedded Human Prostate(dilution: 2.5µg/ml). Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Protocol on data-sheet.

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