Tyrosine hydroxylase is involved in the conversion of phenylalanine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease.
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- Han-Xiang Deng, Yong Shi,Yi Yang,Kreshnik B Ahmeti,Nimrod Miller, Cao Huang,Lijun Cheng,Hong Zhai,Sheng Deng,Karen Nuytemans,Nicola J Corbett,Myung Jong Kim,Hao Deng, Beisha Tang,Ziquang Yang,Yanming Xu,Piu Chan,Bo Huang,Xiao-Ping Gao,Zhi Song,Zhenhua Liu,Faisal Fecto,Nailah Siddique, Tatiana Foroud,Joseph Jankovic,Bernardino Ghetti,Daniel A Nicholson,Dimitri Krainc,Onur Melen,Jeffery M Vance,Margaret A Pericak-Vance,Yong-Chao Ma,Ali H Rajpu t&Teepu Siddique. (2016). Identification of TMEM230 mutations in familial Parkinson's disease. Nature Genetics, doi: 10.1038/ng.3589
- Blount, Andrew L. B.A.; Peled, Ziv M. M.D.; Dexter, Erica L. B.S.; Nagle, Raymond B. M.D., Ph.D.; Maloney, Christopher T. M.D.; Dellon, A Lee M.D., Ph.D. (2008). Sympathetic Nerves in the Tarsal Tunnel: Implications for Blood Flow in the Diabetic Foot. Plastic & Reconstructive Surgery, 122(1):188-191. doi: 10.1097/PRS.0b013e31817742c3
- Ming-He Huang, Hui-Qun Wang, William R. Roeske, Yochai Birnbaum, Yewen Wu, Ning-Ping Yang, Yu Lin, Yumei Ye, David J. McAdoo, Michael G. Hughes, Scott D. Lick, Paul J. Boor, Charles Y. Lui, and Barry F. Uretsky. (2007). Mediating -opioid-initiated heart protection via the 2-adrenergic receptor: role of the intrinsic cardiac adrenergic cell. Am J Physiol Heart Circ Physiol, 293: H376-H384. doi: 10.1152/ajpheart.01195.2006
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