Product Details
Catalog Number: MO22111
Applications: WB, IF
Type: Mouse IgG
Immunogen: Epitope for ?-Synuclein is in the region 61-95 which correspond to the "Non-Amyloid beta Component of Alzheimer's disease amyloid"
Format A: Ascites Fluid
Format B: liquid
Species Reactivity: Human, Mouse, Rat
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$295.00Add to Cart

Image: blots alpha-synuclein antibody on recombinant alpha-synuclein (left lane) and crude extract of mouse brain (right lane, courtesy Rogan Tinsley, Howard Florey Institute, University of Melbourne).

References:
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3. Polymeropoulos, MH et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276: 2045-2047 (1997).
4. Kruger, R et al. Ala30-to-Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nature Genet. 18: 106-108 (1998).
5. Chartier-Harlin, M-C. et al. Alpha-synuclein locus duplication as a cause of familial Parkinson's disease. Lancet 364: 1167-1169 (2004).
6. Singleton, AB.et al. Alpha-synuclein locus triplication causes Parkinson's disease. Science 302: 841 (2003).
7. Culvenor, J.G. et al. Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited: NAC and alpha-synuclein are not associated with Abeta amyloid. Am. J. Pathol. 155:1173-1181 (1999).
8. Ibanez, P. et al. Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease. Lancet 364:1169-1171 (2004).
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10. Cookson MR. Alpha-Synuclein and neuronal cell death. Mol Neurodeg 4:9 (2009).
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