Tau is a relatively low molecular weight member of the microtubule associated protein or MAP. The recombinant protein used to make this antibody is the shortest version of the 8 human tau proteins, so the antibody is expected to bind to all 8 isoforms.
Tau is heavily concentrated in axons of neurons, but may also be found in dendrites and in some non neuronal cells. Much interest has focused on tau as it is a major component of the neurofibrillary tangles of Alzheimer’s disease .
Image: E18 hippocampal neurons were grown for seven days following the protocol. We fixed and immunostained with MO22145 (green) using our standard immunostaining protocol (on datasheet), chicken antibody to α-internexin (CH22101 red) and for DNA (blue). MO22145 stains the neuronal perikarya and process strongly, and does not stain non neuronal cells in these cultures. The α-internexin antibody stains intermediate or 10nm filament bundles in the cytoplasm of these cells.
- Product Reviews
- Related Products
Name Catalog # CCL20 GT34001 Apolipoprotein A-I MO27002 GDNF (Rat) PR15008 GDNF (Rat), Carrier Free PR15008CF ADAM10 (Human), CF PR15036CF-20 APP/Protease Nexin II (Human), CF PR15037CF-10 BACE-1 (Human), CF PR15038CF-50 BACE-1 (Mouse), CF PR15039CF-50 BACE-2 (Mouse), CF PR15040CF-20 DOPA decarboxylase PR15053-10 HGF Human PR15061-5 ApoE R2, CF PR15062CF-50 Kynureninase, CF PR15077CF-10 MANF/ARMET, CF PR15079CF UCHL1 PR22001 NF-L Protein PR22002 GDNF (Human, Mouse) PR27022-10 GDNF (Human, Mouse) PR27022-2 HGF CHO PR27049-10 HGF CHO PR27049-2 HGF Human PR27050-10 HGF Human PR27050-2 Bcl-2 PR27054-1 Bcl-2 PR27054-5 Ubiquitin PR27083-10 Ubiquitin PR27083-50 IL-6 PR27107-20 IL-6 PR27107-5 IL-6, His Tagged PR27108-10 IL-6, His Tagged PR27108-50 Clusterin/APO-J PR27111-10 Clusterin/APO-J PR27111-2 IL-17 PR27113-25 IL-17 PR27113-5 Cathepsin-D PR27139-10 Cathepsin-D PR27139-2 WWOX PR27151-10 WWOX PR27151-2 alpha-Synuclein PR27158-20 Myelin Basic Protein PR27171 Amyloid Beta (A4) Precursor Protein PR27172 Neuron Specific Enolase PR27173 Neurogranin PR27174 Apolipoprotein A-I PR27175 Macrophage Inflammatory Protein-3 alpha (CCL20) PR27176 EMAP II PR27177 Creatine Kinase Brain PR27178 Microtubule-Associated Protein Tau PR27179 Metallothionein 3 PR27180 ICAM-1 RA34006