Product Details
Catalog Number: MO22145
Applications: ICC, WB, IHC, IF
Type: Mouse IgG
Immunogen: Recombinant full length version of the shortest human Tau isoform purified from E. col
Species Reactivity: Human, Mouse, Rat, Primate, Chicken
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$295.00Add to Cart

Tau is a relatively low molecular weight member of the microtubule associated protein or MAP. The recombinant protein used to make this antibody is the shortest version of the 8 human tau proteins, so the antibody is expected to bind to all 8 isoforms.

Tau is heavily concentrated in axons of neurons, but may also be found in dendrites and in some non neuronal cells. Much interest has focused on tau as it is a major component of the neurofibrillary tangles of Alzheimer’s disease . 

Image: E18 hippocampal neurons were grown for seven days following the protocol. We fixed and immunostained with MO22145 (green) using our standard immunostaining protocol (on datasheet), chicken antibody to α-internexin (CH22101 red) and for DNA (blue). MO22145 stains the neuronal perikarya and process strongly, and does not stain non neuronal cells in these cultures. The α-internexin antibody stains intermediate or 10nm filament bundles in the cytoplasm of these cells.