Product Details
Catalog Number: MO22155
Applications: ICC, WB, IHC, IF
Type: Mouse IgG
Immunogen: Amino acids 402-902 of human ALDH1L1 expressed in and purified from E. coli
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat, Chicken, Bovine, Porcine
Downloads: Datasheet (pdf)
Product Sizes
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100ul$295.00Add to Cart

Aldehyde dehydrogenases (ALDH) are a group of enzymes that catalyze oxidation (dehydrogenation) of aldehydes. To date, nineteen ALDH genes have been identified within the human genome. They belong to 15 families in ALDH superfamily. Among these, aldehyde dehydrogenase family 1, member 1 (ALDH1L1) catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. ALDH1L1 expression is tissue-specific and is highly expressed in the liver, representing up to 1% of the total pool of soluble cell proteins in the mammalian liver.

Image: Neuron-glia cell mixed cultures stained with MO22155 (red) and our chicken polyclonal antibody against vimentin: CH22108 (green). Blue is a DNA stain. MO22155 stains astrocytic cell bodies and processes. The fibroblastic cells contain only vimentin and so are green, while astrocytes contain either vimentin and ALDH1L1, so appearing golden, or predominantly ALDH1L1, in which case they appear red..