Aldehyde dehydrogenases (ALDH) are a group of enzymes that catalyze oxidation (dehydrogenation) of aldehydes. To date, nineteen ALDH genes have been identified within the human genome. They belong to 15 families in ALDH superfamily. Among these, aldehyde dehydrogenase family 1, member 1 (ALDH1L1) catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. ALDH1L1 expression is tissue-specific and is highly expressed in the liver, representing up to 1% of the total pool of soluble cell proteins in the mammalian liver.
Image: Neuron-glia cell mixed cultures stained with MO22155 (red) and our chicken polyclonal antibody against vimentin: CH22108 (green). Blue is a DNA stain. MO22155 stains astrocytic cell bodies and processes. The fibroblastic cells contain only vimentin and so are green, while astrocytes contain either vimentin and ALDH1L1, so appearing golden, or predominantly ALDH1L1, in which case they appear red..
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Name Catalog # GFAP CH22102 Vimentin CH22108 Vimentin CH23010 GFAP CH23011 Coronin 1a/p57 CH23017 CD11b (OX-42) CH23021 GDNF Receptor Alpha 1 GT15004 GDNF Receptor Alpha 1 Biotinylated GT15004B GDNF Receptor Alpha 2 GT15005 GDNF Receptor Alpha 2 Biotinylated GT15005B GDNF GT15007 GDNF Biotinylated GT15007B GDNF Receptor Alpha 4 GT15083 SOX2 GT15098 GDNF Receptor Alpha 1 GT15108 GDNF Receptor Alpha 3 GT15123 TROY/TNFRSF19 GT15223 TROY/TNFRSF19, Biotinylated GT15332B SOX2 MO15040 GFAP MO15052 GDNF Receptor Alpha 1 MO15093 GAP43 MO22118 Galectin-3 (LGAS3) MO22119 Aldolase C MO22135 GFAP MO22136 ALDH1L1 MO22143 Aldolase C MO22156 Aldolase C (C-terminus Specific) MO22157 ATPase Na+/K+ transporting alpha 1 MO25023 GFAP MO45001 PTEN-induced kinase/PINK1 RA19013 Survivin RA19022 GFAP RA22101 Coronin 1a/p57 RA22108 GAP43 RA22115 ALDH1L1 RA22119 xCT RA25026 GAP43 RA25086 GDNF Receptor Alpha 3 RA30017