Product Details
Catalog Number: P15049
Applications: WB, IHC
Type: Rabbit IgG
Immunogen: Synthetic peptide of rat CCK A R (a.a. 256 - 267)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ul @ 2 mgs/ml$95.00Add to Cart

The physiologic actions of the cholecystokinin (CCK) family of peptide hormones are mediated through two classes of G protein-coupled receptors GPCR), CCK-A R and CCK-B R. CCK-A R is a 428 amino acid protein with 7 putative transmembrane domains. This GPCR is involved in gall bladder contraction, insulin secretion, and has also been described in specific regions of the central nervous system. CCK-A R has been implicated in pancreatic tumorigenesis as well as the pathogenesis of eating disorders and drug addiction.

Image: CCK-A R staining of rat pancreatic tissue (cryosat sections). Tissue was stained using a Rhodamine Red™ X-conjugated anti-rabbit secondary antibody (red) and counterstained with Fluoro Nissl Green (green).

Rhodamine Red is a trademark of Invitrogen.