Nitric Oxide Synthases are a family of enzymes responsible for the synthesis of nitric oxide from L-arginine and molecular oxygen. There are at least three nitric oxide synthases; NOS I, also known as neuronal NOS or nNOS, NOS II, which is referred to as inducible NOS or iNOS and NOS III, also known as endothelial NOS or eNOS. nNOS plays a role in the upregulation of microglial phospho-p38 MAPK. Such p38 MAPK activation in microglia is consistent with a potential role in the development of morphine antinociceptive tolerance.
nNOS is expressed in the hypothalamus, striatum, cortex, spinal cord and PNS. In ischemic stroke, nNOS activation is linked to Neural Damage.
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Name Catalog # Goat IgG Control GT15900 Vesicular Acetylcholine Transporter GT24286 NOS1AP/CAPON GT41020 Glutamate MO22523 PSD-95/SAP90 MO50000 Somatostatin RA20067 Alpha-MSH/Melanocyte-stimulating hormone RA20074 LHRH/GnRF RA20075 Corticotropin Releasing Hormone Receptor RA20084 nNOS-C-terminus (Neuronal Nitric Oxide Synthase) RA24287 Glutamine Synthetase RA25062 Neurotrypsin RA30051