Product Details
Catalog Number: RA24112
Applications: IHC, IF
Type: Rabbit IgG
Immunogen: Synthetic rat alpha-CGRP coupled to bovine thyroglobulin (BTg) with glutaraldehyde.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Whole serum
Format B: lyophilized
Species Reactivity: Human, Rat
Entrez: 796
UniProt: P01258
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$285.00Add to Cart

Calcitonin gene-related peptide (CGRP) is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin.

Images

CGRP terminal and fiber staining in rat dorsal horn (spinal cord), cryostat sections, ABC / DAB detection.

CGRP terminal and fiber staining in rat dorsal horn (spinal cord), cryostat sections, ABC / DAB detection.

CGRP, IB4 and P2X3 staining in transverse spinal cord sections. A and B show low magnification confocal images of CGRP-IR and IB4 positive. http://www.molecularpain.com/content/8/1/64.

CGRP, IB4 and P2X3 staining in transverse spinal cord sections. A and B show low magnification confocal images of CGRP-IR and IB4 positive. http://www.molecularpain.com/content/8/1/64.