Olig1 and Olig2 are basic-helix-loop-helix (bHLH) transcription factors expressed in the motor neuron progenitor (pMN) domain of the spinal cord that generates motor neurons and oligodendrocytes. Olig1 is involved in the development andmaturation of oligodendrocytes. Olig2 is required for oligodendrocyte and motor neuron specification in the spinal cord.
Olig1 and 2 are also a markers for the most common primary tumors of the human brain are thought to be of glial cell origin. Therefore, there is diagnostic potential of Olig markers to augment identification of oligodendroglial tumors.
Image: Neonatal rat brain lysate showing specific immunolabeling of the ~ 32k Olig2 protein.
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Product ReviewsShipping was a bit delayed-- Neuromics made up for it by shipping extra vials for free Product Name: Olig2, Rabbit – (Cat# RA25081) http://bit.ly/2knYydt Organization: MPI ResearchErica - Jan 24, 2017 - Rating: 4.0
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Name Catalog # CNPase CH23013 Oligodendrocyte Marker O4-Phycoerythrin Labeled FC15013 Olig2 GT15132 MOG GT15141 PDGF R Alpha/CD140A GT15150 MAG/Siglec 4a GT15152 NOGO Receptor GT15154 OMgp GT15200 Mash1 GT15216 Oligodendrocyte Marker O1 MO15001 Oligodendrocyte Marker O4 MO15002 Mash1 MO15048 Olig1,2,3 MO15059 CNP/CNPase MO22144 Olig1 RA14141 CNP RA22120 Caspr2 SP15104