Product Details
Catalog Number: RA30012
Applications: WB, IHC
Type: Rabbit IgG
Immunogen: Synthetic Peptide-Amino acids surrounding Ser 880 of human GLuR2.
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
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50 ug$425.00Add to Cart

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D- aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by -amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD.

Image: GluR2 staining of human brain tissue, cerebellum: Formalin-Fixed Paraffin-Embedded.