Product Details
Catalog Number: RA30031
Applications: IHC
Type: Rabbit IgG
Immunogen: KLH conjugated Synthetic Peptide- C-terminal domain of human FZD7.
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Downloads: Datasheet (pdf)
Product Sizes
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50 ug$435.00Add to Cart

The Frizzled 7 (FZD7)  protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Frizzled family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. Frizzled 7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. Frizzled 7 expression has been reported in brain, gastrointestinal tract, heart, fetal kidney, fetal lung, placenta, skeletal muscle, and various cancers. ESTs have been isolated from a wide variety of normal and cancer libraries.

Image: FZD7 staining of Human Heart Tissue. Formalin-Fixed Paraffin-Embedded (FFPE).

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Images