Product Details
Catalog Number: RA30061
Applications: WB, IHC
Type: Rabbit IgG
Immunogen: KLH-conjugated synthetic peptide corresponding to 16 amino acid peptide from near the carboxy-terminus of human caspase-14.
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
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50 ug$435.00Add to Cart

Caspase-14 is a non-apoptotic caspase which is involved in epidermal differentiation. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

Image:Human Skin (formalin-fixed, paraffin-embedded) stained with Caspase-14  antibody at 5.0 ug/ml followed by Goat anti-rabbit IgG, Biotin-Catalog#:GT30001, alkaline phosphatase-streptavidin and chromogen. Protocol on Datasheet.