Caspase-14 is a non-apoptotic caspase which is involved in epidermal differentiation. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
Image:Human Skin (formalin-fixed, paraffin-embedded) stained with Caspase-14 antibody at 5.0 ug/ml followed by Goat anti-rabbit IgG, Biotin-Catalog#:GT30001, alkaline phosphatase-streptavidin and chromogen. Protocol on Datasheet.
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Name Catalog # Cathepsin D GT15042 Caspase-3 GT15044 Caspase-9 GT15045 Cathepsin B (Human) GT15046 Cathepsin B (Mouse) GT15047 Cathepsin L (Human) GT15048 Cathepsin L (Mouse) GT15049 Cathepsin O GT15197 Cathepsin S GT15198 Cathepsin V GT15199 Cathepsin F MO15096 Cathepsin G MO20021 Caspase-7 MO25036 Caspase-3, active RA15046 Caspase-10/b-Flice 2 RA15047 Caspase-12 RA15048 CARD8 RA30062 CARD9 RA30063