Shank is a novel family of postsynaptic density proteins (PSD) that bind to PSD-95-associated protein GKAP. Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton. Shank1a is a splice variant of Shank1.
Shank1 A has also been found to be associated with L-type Ca2+ channels. Olson et al., J Neurosci. 2005, 25:1050-62; Zhang et al., J Neurosci. 2005, 25:1037-49) the same channels used by photoreceptors for transmitter release.
- Product Reviews
- Product Publications
If you've used this product in a publication, let us know. Email email@example.com, with the publication details and you could be eligible for an Amazon gift card.
- Related Products
Name Catalog # Size Bradykinin Receptor B2 RA14137 100 ul CADM1/SynCAM RA25084 100 ul Calbindin CH22118 100 ul Calbindin MO20016 100 ug Calreticulin MO22164 100 ul Calretinin CH22116 100 ul Calretinin MO20024 100 ul Calretinin MO22166 100 ul Calretinin (IgG1) MO22165 100 ul CaMKII RA18006 100 ul CaMKII2A GT41019 100 ug Cav1.2 Ca2+ channel MO50006 100 ul Cav1.3 Ca2+ channel MO50007 100 ul Cav3.1 Ca2+ channel MO50008 100 ul EpCAM (Epithelial Cell Adhesion Molecule)/Epithelial Specific Antigen MO47063 100 ul MARCKS (Myristoylated Alanine Rich C Kinase Substrate) RA22111 100 ul Neurogranin precursor GT41024 100 ug phospho-Synapsin (Ser9) RA18009 100 ul S-100 MO47059 100 ul SHANK1a C-terminus RA19016 100 ug Striatin RA25067 100 ul Synapsin RA18010 100 ul