Product Details
Catalog Number: GP14100
Applications: IHC
Type: Guinea Pig IgG
Immunogen: YTGSLKPEDAEVFKDSMVPGEK
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Whole serum
Format B: liquid
Species Reactivity: Human, Rat
Entrez: 7442
UniProt: Q8NER1
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
150 ul$475.00Add to Cart
50 ul$215.00Add to Cart

VR1 (vanilloid receptor 1) is a channel activated by capsaicin, the pungent ingredient in hot peppers. It was isolated from sensory neurons. Sequence analysis suggests that VR1 has six transmembrane domains and intracellular N- and C-termini. It shares structural similarities with the family of putative store-operated calcium channels. VR1 is expressed by nociceptive sensory neurons. It is activated by noxious heat and is thought to function as transducer of noxious thermal stimuli.

Supporting Products
NameCatalog #Size
VR1 C-terminus (TRPV1)P14100100 ug Blocking Peptide
Images

VR1-C staining of rat dorsal horn (dilution 1:100).

VR1-C staining of rat dorsal horn (dilution 1:100).

VR1-C staining of rat dorsal horn (dilution 1:100).

VR1-C staining of rat dorsal horn (dilution 1:100).

TRPV1 staining of mouse inferior olive using Cy3-conjugated donkey anti-rabbit secondary antibodies (red color) and DAPI (blue) as a nuclear counterstain.

TRPV1 staining of mouse inferior olive using Cy3-conjugated donkey anti-rabbit secondary antibodies (red color) and DAPI (blue) as a nuclear counterstain.

TRPV1 staining of mouse inferior olive using Cy3-conjugated donkey anti-rabbit secondary antibodies (red color) and DAPI (blue) as a nuclear counterstain.

TRPV1 staining of mouse inferior olive using Cy3-conjugated donkey anti-rabbit secondary antibodies (red color) and DAPI (blue) as a nuclear counterstain.

(J Dent Res 85(1):49-53, 2006) : Evaluation of the expression patterns of TLR4 and CD14 in trigeminal sensory neurons. White arrows depict examples of neurons expressing both markers for each row of three images, and yellow arrows depict examples of neurons that express one but not both markers.

(J Dent Res 85(1):49-53, 2006) : Evaluation of the expression patterns of TLR4 and CD14 in trigeminal sensory neurons. White arrows depict examples of neurons expressing both markers for each row of three images, and yellow arrows depict examples of neurons that express one but not both markers.