Product Details
Catalog Number: GT41020
Applications: IHC, E
Type: Rabbit IgG
Immunogen: Peptide with sequence PSKTKYNLVDDGH-C, from the N Terminus of the protein sequence according to NP_055512.1; NP_001158229.1
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat
Entrez: 9722
UniProt: O75052
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$325.00Add to Cart

NOS1AP or Capon is an adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. It competes with PSD95 for interaction with nNOS, and overexpression results in a loss of PSD95/nNOS complexes in transfected cells. CAPON may influence nNOS by regulating its ability to associate with PSD95/NMDA receptor complexes.

Coding variation in the NOS1AP gene could increase susceptibility to psychiatric disorders like schizophrenia and autism spectrum disorders (ASDs) and obsessive-compulsive disorder (OCD).

Supporting Products
NameCatalog #Size
NOS1AP/CAPONP41020100 ug Blocking Peptide
Images
NOS1AP/Capon (dilution: 4.0 µg/ml) staining of paraffin embedded Human Brain. Steamed antigen retrieval with Tris/EDTA buffer pH 9.5, HRP-staining.

NOS1AP/Capon (dilution: 4.0 µg/ml) staining of paraffin embedded Human Brain. Steamed antigen retrieval with Tris/EDTA buffer pH 9.5, HRP-staining.

NOS1AP/Capon (dilution: 4.0 µg/ml) staining of paraffin embedded Human Brain. Steamed antigen retrieval with Tris/EDTA buffer pH 9.5, HRP-staining.

NOS1AP/Capon (dilution: 4.0 µg/ml) staining of paraffin embedded Human Brain. Steamed antigen retrieval with Tris/EDTA buffer pH 9.5, HRP-staining.