Product Details
Catalog Number: GT41026
Applications: IHC
Type: Goat IgG
Immunogen: Peptide with sequence DEATKKACYSKGKS (corresponding to a part of the extra-cellular domain) from the internal region of the protein sequence according to NP_003957.1.
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 9037
UniProt: Q13591
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 ug$325.00$250.00Add to Cart

Members of the semaphorin protein family are involved in axonal guidance during neural development. Semaphorin 5a is thought to have a bifunctional role in axon guidance, exerting both attractive and inhibitory effects on developing axons associated with limbic function. The thrombospondin repeats of Semaphorin 5a physically interact with both heparan sulfate proteoglycans and chondroitin sulfate proteoglycans, inducing attractive and inhibitory guidance cues, respectively. The biological responses to Semaphorin 5a are induced through binding to its high-affinity receptor, plexin B3, triggering intracellular signaling through Me

Semaphorine 5A plays a role in autism, reducing the ability of neurons to form connections with other neurons in certain brain regions

Supporting Products
NameCatalog #Size
Semaphorin 5AP41026100 ug Blocking Peptide
Images
Semaphorin5a  (dilution: 2.5 µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining Protocol on Data-sheet.

Semaphorin5a (dilution: 2.5 µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining Protocol on Data-sheet.

Semaphorin5a  (dilution: 2.5 µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining Protocol on Data-sheet.

Semaphorin5a (dilution: 2.5 µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining Protocol on Data-sheet.