Product Details
Catalog Number: KF17203
Applications: Apoptosis Detection
Type: Kit
Storage: Store at 2°C-8°C.
Shipping: Refrigerated (Polar Packs)
Species Reactivity: All
Downloads: Datasheet (pdf)
Product Sizes
SizeList PricePriceCart
100 Tests$561.00Add to Cart
25 Tests$195.00Add to Cart

Polycaspase and Caspase in vitro apoptosis kits make it easy to measure cell death and apoptosis in cultured neurons and many other cell types. Just add the reagent to the media, let it incubate 1- 4 hours, wash the cells and read with a fluorescence plate reader, microscope, or flow cytometer.  Apoptotic cells fluoresce red or green.

Images

Monocytes of Alzheimer’s disease (AD) patients (left pictures) become apoptotic and therefore cannot properly process amyloid beta. Control monocytes (right) differentiate into macrophages and efficiently phagocytize amyloid beta. Cells were labeled with Polycaspase Assay Kit to stain caspase-3-positive cells green (bottom). In vitro staining with this kit distinguishes apoptotic AD monocytes (bottom left) from healthy control cells (bottom right). Data courtesy of Dr. Milan Fiala, UCLA.

Monocytes of Alzheimer’s disease (AD) patients (left pictures) become apoptotic and therefore cannot properly process amyloid beta. Control monocytes (right) differentiate into macrophages and efficiently phagocytize amyloid beta. Cells were labeled with Polycaspase Assay Kit to stain caspase-3-positive cells green (bottom). In vitro staining with this kit distinguishes apoptotic AD monocytes (bottom left) from healthy control cells (bottom right). Data courtesy of Dr. Milan Fiala, UCLA.