ATPase Na+/K+ transporting alpha 1 is an integral membrane protein complex that hydrolyzes ATP to maintain the transmembrane gradients of Na+ and K+ found in most mammalian cells. The enzyme is comprised of an alpha and beta subunit. The alpha-polypeptide has been shown to be the catalytically active subunit, wherease the Beta-polypeptide appears to be necessary for the assembly and transport of the sodium pump to the plasma membrane. This ATPase Na+/K+ transporting alpha 1 is expressed in both neuronal and non-neuronal cells
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