Octamer-binding transcription factor 4 (Oct-4) or POU domain, class 5, transcription factor 1 (POU5F1) is a member of the POU homeodomain family of transcription factors. It is involved in both the maintenance and regulation of pluripotency in embryonic stem cells and in germ cells. MO47035 is designed and developed for the sensitive detection of Oct-4 through immunohistochemistry applications. Oct-4 expression has been shown to be present in seminoma, germinoma, dysgerminoma, embryonal carcinoma, and gonadoblastoma, and may be associated with tumorigensis in studies.
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