SALL4 Antibody may be used as a marker to detect acute myeloid leukemia, B-cell acute lymphocytic leukemia, intratubular germ cell neoplasia, seminomas/dysgerminomas, and/or yolk sac tumors (both pediatric and postpubertal). It is designed and developed to sensitively stain for the presence and/or absence of SALL4 expression which is a zinc finger transcription factor generally found in germ cells and human blood progenitor cells. It's functional involvement is in modulating Oct-4 to maintain embryonic stem cell pluripotency.
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