Product Details
Catalog Number: RA25025
Applications: IHC, IP
Type: Rabbit IgG
Immunogen: The epitope recognized by this antibody maps to a region between residues 2150 and 2200 of human spectrin, beta, non-erythrocytic 2 (spinocerebellar ataxia 5 ) using the numbering given in entry NP_008877.1
Storage: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Shipping: Frozen (Polar Packs)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human
Entrez: 6712
UniProt: O15020
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$295.00Add to Cart

Mutations in spectrins are a previously unknown cause of ataxia and neurodegenerative disease that affect membrane proteins involved in glutamate signaling.

Spectrin-beta IIIs have been recognized as ataxia disease genes and their mutations cause spinocerebellar ataxia type 5 (SCA5).

Images

Detection of Spectrin Beta-III in human hepatocytes

Detection of Spectrin Beta-III in human hepatocytes

Detection of Human Spectrin Beta III (SPTBN2/SCA5) by Western Blot of Immunoprecipitates.

Detection of Human Spectrin Beta III (SPTBN2/SCA5) by Western Blot of Immunoprecipitates.