Mammalian target of rapamycin (mTOR) regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, and transcription. It is is activated in response to nutrients, growth factors and cellular energy.
Dysregulated mTOR signaling has been implicated in major diseases These include: cancer, metabolic disorders, neurological diseases, and inflammation. For example, findings demonstrate mTOR signaling hyperactivity in Alzheimer's Disease (AD) brains.
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