Carcinoma-associated fibroblasts (CAFs) have recently been implicated in important aspects of epithelial solid tumor biology such as neoplastic progression, tumor growth, angiogenesis, and metastasis. Immunophenotypes of CAFs are different from Adenocarcinomas in Lung Cancer. These CAFs have therefore have separate and important prognostic value.
Cells are prepared and manufactured in an ISO 9001:2015 certified environment and ISO 5 cleanroom.
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- Namrata Bora-Singhal, Durairaj Mohankumar, Biswarup Saha, Christelle M. Colin, Jennifer Y. Lee, Matthew W. Martin, Xiaozhang Zheng, Domenico Coppola, and Srikumar Chellappan. (2020). Novel HDAC11 Inhibitors Suppress Lung Adenocarcinoma Stem Cell Self-Renewal and Overcome Drug Resistance by Suppressing Sox2. Scientific Reports, 10:4722. doi: 10.1038/s41598-020-61295-6
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