Visinin-like protein 1 (VSNL1) is a small Calcium binding protein which is very abundant in the nervous system and is found only in neurons, though different neurons have different levels of expression (4, 5). It is particularly concentrated in cerebellar Purkinje cells, and tends to be most abundant in perikarya and dendrites. The protein was discovered independently by several groups and is therefore also sometimes known as hippocalcin-like protein 3, HLP3, HPCAL3, HUVISL1, VLP-1, VILIP and VILIP-1. The protein belongs to the large superfamly of calmodulin and paravalbumin type proteins which function by binding Calcium ions. Calcium binding alters the confomation of these proteins and allow them to interact with other binding partners, the properties of which they may alter. Visinin-like protein 1 has four "EF hand" domains, which are negatively charged helix-turn-helix peptides which are responsible for Calcium binding. Visinin-like protein 1 is 191 amino acids in size and has a molecular weight on SDS-PAGE of 22kDa.
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Name Catalog # GFAP CH22102 MAP2 (Microtubule assoc. protein 2) CH22103 Neurofilament NF-H CH22104 Nestin CH23001 Neuron Specific Enolase (NSE)/ENO2 CH23003 GFAP CH23011 Peripherin CH23016 PGP9.5 175-191 GP14104 NT-3 GT15000 GDNF Receptor Alpha 1 GT15004 GDNF Receptor Alpha 1 Biotinylated GT15004B GDNF Receptor Alpha 2 GT15005 GDNF Receptor Alpha 2 Biotinylated GT15005B GDNF GT15007 GDNF Biotinylated GT15007B CNTF GT15028 CNTF Receptor Alpha GT15029 Artemin GT15066 TrkB GT15080 GDNF Receptor Alpha 4 GT15083 GDNF Receptor Alpha 1 GT15108 NT-3 GT15128 TrkA GT15153 NOGO Receptor GT15154 CXCL8/IL-8 GT15156 Cathepsin V GT15199 FOXC1 GT41004 TrkC MO15000 Nestin MO15012 TrkA MO15018 Artemin MO15021 TrkB MO15025 TrkA MO15034-100 TrkA MO15034-500 TrkB MO15042 Nestin MO15056 CXCR1/IL-8 RA MO15072 CXCR2/IL-8 RB MO15073 mGluR5 MO15118 Synaptophysin MO20000 PGP9.5 MO20002 Neurofilament NF-H MO22103 MAP2 (Microtubule assoc. protein 2) MO22116 Rhodopsin (B630) MO22127 Rhodopsin (A531) MO22128 Visinin-like protein 1/VSNL1 MO22132 Arrestin-1 MO22141 Glutamate MO22523 RPE65 [401.8B11.3D9] MO25011 3-OHKYN MO25014 Bestrophin MO25024 MAP2 (Microtubule assoc. protein 2) MO30000 PSD-95/SAP90 MO50000 PGP9.5 RA12103 mGluR6 RA13105 P2Y2 RA14103 Alpha 2a Adrenergic Receptor RA14110 mGluR5 RA16100 phospho-TrkA(Tyr490) RA18018 Artemin RA19009 SHANK1a N-Terminus RA19015 SHANK1a C-terminus RA19016 Alpha 2c Adrenergic Receptor RA19064 mGluR1 alpha RA19065 GFAP RA22101 OPA1 RA25019 mGluR6/7 RA25041 Glutamine Synthetase RA25062 mGluR6 RA30046