Product Details
Catalog Number: CH23002
Applications: ICC, WB, IHC
Type: Chicken IgY
Dilutions: ICC 1:100-1:200; IHC 1:100-1:200; WB 1:250-1:500
Immunogen: Peptide common to mouse (O09118) and human (O95631) Netrin-1
Storage: Store at 4°C in the dark
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$99.00Add to Cart

Murine netrin-1 precursor is a 67,768 dalton protein (604 amino acids) expressed by subpopulations of cells within the developing CNS, as well as in various non-neural tissues, including the gut, liver, heart, and prostate. In the embryonic CNS, netrin-1 is expressed by cells of the floor plate, and acts to attract axons of commissural neurons from the dorsal horn gray matter. Netrin-1 is also believed to play a role in the growth of motor axons in the PNS.

Images
Dissociated cell cultures of an e13 mouse brain showing Netrin-1 (green staining) in neuronal precursor cells.

Dissociated cell cultures of an e13 mouse brain showing Netrin-1 (green staining) in neuronal precursor cells.

Dissociated cell cultures of an e13 mouse brain showing Netrin-1 (green staining) in neuronal precursor cells.

Dissociated cell cultures of an e13 mouse brain showing Netrin-1 (green staining) in neuronal precursor cells.

Immunohistochemical colocalization of netrin-1 and endothelial markers. Paraformaldehyde-fixed frozen tissue sections were stained with anti-netrin-1 antibody (red stain) and anti-Von Willebrand Factor (VWF) antibody (green stain) as described in MATERIALS AND METHODS. Nuclei were stained blue with DAPI. doi:10.1152/ajprenal.00508.2007.

Immunohistochemical colocalization of netrin-1 and endothelial markers. Paraformaldehyde-fixed frozen tissue sections were stained with anti-netrin-1 antibody (red stain) and anti-Von Willebrand Factor (VWF) antibody (green stain) as described in MATERIALS AND METHODS. Nuclei were stained blue with DAPI. doi:10.1152/ajprenal.00508.2007.

Immunohistochemical localization of netrin-1 in renal cell carcinoma (RCC) tissues. A. Secondary antibody control showing no staining. B. Normal adjacent tissues do not show any staining for netrin-1. C. Stage I RCC shows staining for netrin-1. D. Stage II RCC shows staining for netrin-1. E&F. doi: 10.3109/1354750X.2010.541564

Immunohistochemical localization of netrin-1 in renal cell carcinoma (RCC) tissues. A. Secondary antibody control showing no staining. B. Normal adjacent tissues do not show any staining for netrin-1. C. Stage I RCC shows staining for netrin-1. D. Stage II RCC shows staining for netrin-1. E&F. doi: 10.3109/1354750X.2010.541564