Product Details
Catalog Number: CH23011
Applications: ICC, WB, IHC, IF
Type: Chicken IgY
Dilutions: IHC 1:50-1:100; ICC 1:50-1:100
Immunogen: Recombinant Protein
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse
Downloads: Datasheet (pdf)
Product Sizes
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200 ul$285.00Add to Cart

Human GFAP is a 49,749 dalton protein (432 amino acids) expressed in astrocytes. GFAP is an intermediate filament protein and acts as an intracellular structural component of the cytoskeleton. During embryonic and fetal life, GFAP is also expressed by radial glial cells of the CNS. Various mutations of the GFAP gene in humans produce Alexander's disease, one of the leukodystrophies.

 GFAP: Customer Publications

Images
A tissue section through an e18 mouse brain showing GFAP (brown) staining of radial glial cells (a.k.a. Bergman fiber of the cerebellum).

A tissue section through an e18 mouse brain showing GFAP (brown) staining of radial glial cells (a.k.a. Bergman fiber of the cerebellum).

A tissue section through an e18 mouse brain showing GFAP (brown) staining of radial glial cells (a.k.a. Bergman fiber of the cerebellum).

A tissue section through an e18 mouse brain showing GFAP (brown) staining of radial glial cells (a.k.a. Bergman fiber of the cerebellum).