Product Details
Catalog Number: MO18004
Applications: IHC
Type: Mouse IgG
Immunogen: Produced by immunizing BALB/c mice with blast cells of a chronic myeloid leukemia patient.
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$332.00Add to Cart

CD34 is a type I transmembrane glycophosphoprotein expressed by hematopoietic stem/progenitor cells (HSCs).

CD34 may also stimulate proportions of adult human HSCs to differentiate into full-fledged neurons. This may open new possibilities for a high-yield production of neurons from bone marrow.

In tumors, CD34 is found in alveolar soft part sarcoma, preB-ALL (positive in 75%), AML (40%), AML-M7 (most), dermatofibrosarcoma protuberans, gastrointestinal stromal tumors, giant cell fibroblastoma, granulocytic sarcoma, Kaposi’s sarcoma, liposarcoma, malignant fibrous histiocytoma, malignant peripheral nerve sheath tumors, mengingeal hemangiopericytomas, meningiomas, neurofibromas, schwannomas, and papillary thyroid carcinoma.

Image: CD34 staining of paraffin-embedded human capillary hemangioma.

 

 

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