Product Details
Catalog Number: MO25042
Applications: WB, IHC, E
Type: Mouse IgG
Immunogen: Residues 140-160 of purified human ApoE (LDLR receptor binding site)-WUE4
Format A: Protein G Purified
Format B: liquid
Species Reactivity: Human
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$325.00Add to Cart

Apolipoprotein E (ApoE) is a major component of specific lipoproteins called very low-density lipoproteins (VLDL). A major function of VLDLs is to remove excess cholesterol from the blood and carry it to the liver for processing. Maintaining normal levels of cholesterol is essential for the prevention of cardiovascular diseases, including heart attacks and strokes. Apolipoprotein E is a type of lipoprotein. Apolipoprotein E is associated with several cardiovascular disorders. There are three isoforms (slightly different forms) of the ApoE lipoprotein. These three isoforms are known as ApoE2, E3 and E4. ApoE2 seems to be one of several genetic factors that plays a part in increased risk of heart attacks and strokes and ApoE4 is a risk factor for coronary artery disease. As well, ApoE4 has been been suggested to play a role in type 2 Alzheimer disease.

Image: Detection of ApoE in human tissue lysate using NB110-60531.
Lane 1: liver
Lane 2: brain

Images