Product Details
Catalog Number: RA19006
Applications: WB, IHC
Type: Rabbit IgG
Immunogen: AIVEALNGKEVAAQVKAPLVLKD (a.a. 167-189 of human PARK7)
Format A: Affinity Purified
Format B: liquid
Species Reactivity: Human, Mouse, Rat
Downloads: Datasheet (pdf)
Product Sizes
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100 ul$250.00Add to Cart

Four chromosomal loci (PARK2, PARK6, PARK7, and PARK9) associated with autosomal recessive, early onset parkinsonism are known. Positional cloning within the refined PARK7 critical region recently identified mutations in the DJ-1 gene in PARK7-linked families. Mutations in the PARK7/DJ-1 gene cause autosomal-recessive Parkinson’s disease. 

Image: DJ-1 Western Blot of rat primary cortical astrocytes. Red pseudo-coloring shows beta actin around 42kDa and DJ-1 around 24kDa. This blot was also labeled for heme oxygenase 1 which is pseudo-colored green around 27kDa. Courtesy of Amanda Titler, Duquesne University.