Neuropeptide Y is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. Two major subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria. NPY receptors, such as NPY1R, have been identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, and aortic smooth muscle.
- Product ReviewsShipping was fast and customer service was excellent!! Product Name: NPY Y1 Receptor (Cat# RA24506) http://bit.ly/1hOerl8 Organization: University of North CarolinaRhiannon Thomas - Oct 24, 2013 - Rating: 5.0
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- Product Publications
- Tyler S. Nelson, Weisi Fu, Renée R. Donahue, Gregory F. Corder, Tomas Hökfelt, Ronald G. Wiley & Bradley K. Taylor. (2019). Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn. Scientific Reports volume 9, Article number: 7248. https://doi.org/10.1038/s41598-019-43493-z
- Matthew Klompusa, Winnie Hoa, Keith A. Sharkeya and Derek M. McKaya. (2010). Antisecretory effects of neuropeptide Y in the mouse colon are region-specific and are lost in DSS-induced colitis. Regulatory Peptides, Volume 165, Issues 2-3, Pages 138-145. doi: 10.1016/j.regpep.2010.05.014
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